Sickle-cell disease neonatal screening activities started in 2016 in three partner healthcare structures in Pointe-Noire. A laboratory was equipped and put into operation for analyzing samples. About 100 staff members from maternity units were trained in sickle-cell disease, as well as in sampling and patient information techniques During prenatal consultations, about 2,000 pregnant women were told about the need to screen their child at birth and were informed that this screening was free.